Registered Nurse Salary in Irvine, CA (2026)

Updated 18 hours ago · 631 observed active listings

The salary landscape for Registered Nurses in Irvine, CA, is shaped by a combination of high demand and a competitive employer environment. With 631 open positions, the job market reflects a robust need for healthcare professionals, driving salaries upward. The trimmed average salary of $98,462 positions itself between the lower-bound 10th percentile at $40,000 and the upper-bound 90th percentile at $140,000, revealing a significant wage spread that highlights both entry-level roles and highly specialized positions. This wide salary range indicates a diverse hiring landscape where employers are competing for skilled candidates, particularly as healthcare needs continue to evolve post-pandemic. The clustering of employers, such as KPC GLOBAL MEDICAL CENTERS INC. and EVN Dialysis Center LLC, further intensifies competition, leading to potential negotiation leverage for candidates who may find themselves in a strong position given the current job openings and their own qualifications.

Salary Distribution

Key Insights

• The wide P10–P90 spread ($40,000–$140,000) reflects a significant variance in experience and specialization levels among Registered Nurses, indicating potential for negotiation based on individual qualifications.
• With a trimmed average salary of $98,462, nurses are positioned within a competitive range, suggesting that many positions are likely offering above the median to attract talent amid a tight job market.
• The concentration of active employers in the area, including multiple healthcare facilities, creates a competitive environment that can uplift salary offers, particularly for nurses with in-demand specialties.
• The presence of 631 open positions signals a high demand for Registered Nurses in Irvine, which can empower candidates during salary negotiations, as employers might be willing to enhance offers to secure qualified professionals.
• The gap between the 25th percentile ($60,000) and the 75th percentile ($140,000) indicates that there are substantial opportunities for career progression and salary growth as nurses gain experience and specialized skills.

Current Registered Nurse Jobs in Irvine

• Registered Nurse - Operating Room
  Apidel Technologies · Irvine, Orange County
  $81,060 – $81,060
• Registered Nurse II, Full-time, Night Shift (8 Hours)
  KPC GLOBAL MEDICAL CENTERS INC. · Anaheim Hills, Orange County
  $86,871 – $86,871
• School Registered Nurse - 1:1 Care - $49-58 per hour
  Cross Country Education · Anaheim Hills, Orange County
  $80,777 – $80,777
• Registered Nurse II, Full-time, Evening Shift (8 Hours)
  KPC GLOBAL MEDICAL CENTERS INC. · Anaheim Hills, Orange County
  $87,563 – $87,563
• Registered Nurse
  PREMIERE HCSTAFFING · Bristol, Orange County
  $80,129 – $80,129
• School Registered Nurse
  Ro Health · East Irvine, Orange County
  $71,000 – $83,000
• Registered Nurse (RN)
  Wellpath · Santa Ana, Orange County
  $90,942 – $90,942
• Home Health Registered Nurse (RN)
  Healthways Home Health Services Inc · Irvine, Orange County
  $76,425 – $76,425
• Travel Registered Nurse ICU Job
  Jobscast · Orange, Orange County
  $92,369 – $92,369
• Registered Nurse Spectrum Home
  EVN Dialysis Center LLC · Santa Ana, Orange County
  $92,812 – $92,812

Frequently Asked Questions

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